Qimanguli et al. developed a heat-shrinkable electrospun fibrous tape for restoring structure and function of loose soft tissue

Fig1. Schematic illustrations of the heat-shrinkable electrospun fibrous tape contraction behavior and loose soft tissue repairing process

 

     Qimanguli et al. successfully developed a heat-shrinkable electrospun fibrous tape and firstly applicated for loose soft tissue repairing. The HS-EFT made from amorphous polymer PLGA contracted slowly retracting the loose tissue regaining normal tissue structure. The retractive force was transformed into mechanical stimulation which promotes the nuclear transfer co-transcriptional factor YAP, and eventually making new ECM deposition. The heat-shrinkable fibrous tape is highly promising as a novel biomaterial for soft tissue repairing both structurally and functionally.

 

Journal page number: Adv. Funct. Mater.2021, 31, 2007440.

Paper links: https://onlinelibrary.wiley.com/doi/abs/10.1002/adfm.202007440