Zhen Wang et al. reviewed pharmaceutical electrospinning and 3D printing scaffold design for bone regeneration

Fig 1. Therapeutic agents delivery based on 3D printing and electrospinning technologies for responsive bone regeneration.

 

Ph.D. zhen Wang et al. mainly summarized the points of scaffold design as well as applications for bone regeneration based on both electrospinning and 3D bioprinting（Figure1）. It first introduces biological characteristics of bone regeneration and summarizes the applications of different types of material and the considerations for bone regeneration in detail. The review then discussed electrospinning nanofibrous scaffold applied for the bone regenerative engineering with various properties, components and structures. Meanwhile, diverse design in the 3D bioprinting scaffolds for osteogenesis especially in the role of drug and bioactive factors delivery are assembled. Finally, they discuss challenges and future prospects in the development of electrospinning and 3D bioprinting for osteogenesis and prominent strategies and directions in future.

 

Journal page number: Journal of Controlled Release.2021,329,237-256.

Paper links: https://www.sciencedirect.com/science/article/pii/S0169409X21001630