庄亚平,博士,助理研究员。硕士毕业于中国科学院化学所,师从吴德成教授,博士毕业于复旦大学高分子科学系丁建东/俞麟教授课题组。2020年至2023年在上海交通大学医学院附属瑞金医院/上海市伤骨科研究所从事博士后研究。主要研究领域聚焦于介入生物材料,包括功能化微球、温敏性聚酯/聚多肽水凝胶及化学水凝胶。已在国际著名学术期刊上发表论文二十余篇,包括Nat. Commun., Adv. Mater., Adv. Funct. Mater., Sci. Adv., Bioact. Mater., Chem. Eng. J., ACS Appl. Mater. Interfaces, Adv. Drug Deliver. Rev.等期刊上,主持国家自然科学基金青年项目,博士后科学基金面上资助,上海市卫健委青年项目、瑞金医院青年培育计划等多项基金,入选2020年上海交通大学医学院博士后激励计划和2021年上海市“超级博士后”等人才项目。
研究方向
1. 介入纳米刀联合生物材料在组织再生、肿瘤免疫等领域的应用;
2. 功能化水凝胶微球在骨、肌腱粘连等组织再生医学中的应用;
3. 长效缓释及靶向递送系统开发。
代表性科研论文
1. X.Y. Liu#, Y.P. Zhuang#, W. H, Q.G. Shan, Z.Y. Wu, X.Y. Ding, Z.L. Qiu, W.G. Cui*, Z.M. Wang*, Interventional hydrogel microsphere vaccine as an immune amplifier for activated antitumor immunity after ablation therapy, Nature communications (2023)
2. F. Lin#, Y.P. Zhuang#, L. Xiang, T.J. Ye, Z. Wang, L.X. Wu, Y.P. Liu, L.F. Deng, W.G. Cui*, Localization of Lesion Cells and Targeted Regulation of the Mitochondria via Heat Transfer Chinese Screw-threaded Microneedles, Advanced Functional materials (2023)
3. Z.R. Fu, Y. Lai, Y.P. Zhuang*, F. Lin*, Injectable heat-sensitive nanocomposite hydrogel for regulating gene expression in the treatment of alcohol-induced osteonecrosis of the femoral head, ALP Bioengineering (2023)
4. B.F. Zhao#, Y.P. Zhuang#, Z.M. Liu, J.Y. Mao, S.T. Qian, Q.Y. Zhao, B.L. Lu, X.Y. Mao, L.C. Zhang, Y.G. Zhang*, W.G. Cui*, X.M. Sun*, Regulated Extravascular Microenvironment via Reversible Thermosensitive Hydrogel for Inhibiting Calcium Influx and Vasospasm, Bioactive materials (2022)
5. Y.P. Zhuang, W.G. Cui*, Biomaterial-based delivery of nucleic acids for tissue regeneration, Advanced Drug Delivery Reviews (2021)
6. Y.P. Zhuang, X.W. Yang, Y.M. Li, Y.P. Chen, X.C. Peng, L. Yu*, J.D. Ding, Sustained Release Strategy Designed for Lixisenatide Delivery to Synchronously Treat Diabetes and Associated Complications, ACS Applied Materials & Interfaces (2019)
7. Y.P. Zhuang, H. Sheng, F. Yang, X. Wang, D.C. Wu, Synthesis and characterization of PLGA nanoparticle/4-arm-PEG hybrid hydrogels with controlled porous structures, RSC advances (2016)