取得成果:
1.发表文章
(1) J Chen#, Y Ma#, Z Yang, H Lang, Y Zhang, H Xia, X Tu, B Liu. TNFAIP3 ameliorates the degeneration of inflammatory human nucleus pulposus cells by inhibiting mTOR signaling and promoting autophagy. Aging. 2020, 12, 24242–24254.
(2) X Wang#, Y Ma#, J Chen#,Y Jiao#, G Liu, P Wang, B Wang, M Taketo, T Bellido, X Tu. A novel decellularized matrix of Wnt signaling-activated osteocytes accelerates the repair of critical-sized parietal bone defects with osteoclastogenesis, angiogenesis, and neurogenesis. Bioactive materials. 2022, 21, 110–128.
(3) G Liu#, J Chen#, Y Ma, X Wang, Y liu, X Tu. Functionalized 3D-printed ST2/Gelatin Methacryloyl/Polcaprolactone Scaffolds for Enhancing Bone Regeneration with Vascularization. International journal of molecular sciences. 2022, 23, 8347.
(4) Y Xin, J Chen, H Zhang, R Ostrowski, Y Liang, J Zhao, X Xiang, F Liang, W Fu, H Huang, X Wu, J Su, J Deng, Z He. Dexras1 induces dysdifferentiation of oligodendrocytes and myelin injury by inhibiting the cAMP-CREB pathway after subarachnoid hemorrhage. Cells. 2022, 11, 2976.
(5) Y Liu, X Ruan, J Li, B Wang, J Chen, X Wang, P Wang, X Tu. The Osteocyte Stimulated by Wnt Agonist SKL2001 Is a Safe Osteogenic Niche Improving Bioactivities in a Polycaprolactone and Cell Integrated 3D Module. Cells. 2022, 11, 831.
(6) P Wang, X Wang, B Wang, X Li, Z Xie, J Chen, T Honjo, X Tu. 3D printing of osteocytic Dll4 integrated with PCL for cell fate determination towards osteoblasts in vitro. Bio-Design and Manufacturing volume. 2022, 5, 497–511.
(7) X Wang, Y Ma, J Chen, G liu, Y Song, X Tu. Wnt3a-induced ST2 decellularized matrix ornamented PCL scaffold for bone tissue engineering. Biocell. 2022, 46, 2089-2099.
(8) Y Zhang, W Yi, H Xia, H Lan, J Chen, Z Yang, F Han, P Tang, B Liu. A20 regulates inflammation through autophagy mediated by NF-κB pathway in human nucleus pulposus cells and ameliorates disc degeneration in vivo. Biochemical and biophysical research communications. 2021, 549, 179–186.
2.主持科研项目:
(1) 重庆市教委,“基于生物打印构建生物活性人工骨的实验研究”, CYB20167, 1万元, 2019.09 - 2022.05, 已结题
(2)上海瑞金医院,“3D 生物打印构建基于多功能成骨微环境的骨再生材料及修
复的研究”,2万元, 2023.1 - 2023.12, 在研
3.取得专利:
硬材料与细胞一体化三维生物打印方法、骨修复功能模块和骨类器官的制备方法与应用”(专利号:202111169004.9)。
4 获奖:
2012-11 评为“优秀学生干部”
2014-05 获得“国家励志奖学金”
2016-06 评为“优秀实习生”
2016-06 评为“优秀毕业生”
2017-12 评为“优秀党支部书记”
2021-05 获得“甲等奖学金”
2021-07 评为“优秀共产党员”
2022-04 评为“优秀毕业生”
2022-04 评为“重庆市优秀学生干部”