卢敏，副研究员/博导，上海海外高层次人才引进专家。2014年毕业于上海交通大学,生物学专业。2015年至2019年在哈佛大学医学院、麻省总医院 Wellman Center for Photomedicine 从事博士后研究,期间主要工作是基于新兴的激光杀菌技术治疗临床多重耐药细菌感染方面的研究,解决的临床感染问题包括骨科感染、医院获得性感染、肺感染、胃部感染、生殖系统感染和尿路感染等。2019年8月入职上海交通大学医学院附属瑞金医院、上海市伤骨科研究所，组建激光医学创新团队，职称副研究员，博士生导师。目前已在激光杀菌技术领域和天然抗菌药物领域发表SCI论文十余篇,包括Science, Sci. Transl. Med., Commun. Biol., J. Infect. Dis., Virulence, Front. Microbiol., Front. Cell Dev. Biol.和J. Biophotonics等；授权国家发明专利4项；多次受邀参加SPIE、MHSRS等国际会议，并做大会报告。2015年至今，担任J. Infect. Dis.、J. Nanobiotechnol.、Front. Microbiol.和Antimicrob. Agents. Ch.等近20个国际学术期刊的审稿人；2017年至今，担任微生物领域国际重要刊物Front Microbiol（IF＞5）助理编辑。
研究方向
①治疗临床多重耐药细菌感染的新颖激光杀菌技术开发；
②杀菌、抗炎、组织修复等多功能生物材料制备与应用；
③仿生纳米材料及其纳米疫苗在感染类疾病领域的应用。
已发表期刊文章
1. M. Lu, Y. Wang, M. X. Wu. Bacteria-Specific “Pro-photosensitizer” for Killing Multidrug-Resistant Staphylococcus aureus and Pseudomonas aeruginosa. Commun. Biol. 4, 408 (2021).
2. M. Lu, S. Wang, T. Wang, S. Hu, B. Bhayana, M. Ishii, Y. Kong, Y. Cai, T. Dai, W. Cui, and M. Wu. Bacteria-specific phototoxic reactions triggered by blue light and phytochemical carvacrol. Science Translational Medicine, 13, eaba3571 (2021).
3. J. Wang, P. Li, Y. Yu, Y. Fu, H. Jiang, M. Lu, Z. Sun, S. Jiang, L. Lu, M. Wu, Pulmonary surfactant-biomimetic nanoparticles potentiate heterosubtypic influenza immunity. Science 367, 1-12 (2020).
4. L. Cheng, Z. Cai, J. Zhao, F. Wang, M. Lu, L. Deng, W. Cui. Black phosphorus-based 2D materials for bone therapy. Bioact. Mat. 5, 1026-1043 (2020).
5. L. Cheng, Z. Chen, Z. Cai, J. Zhao, M. Lu, J. Liang, F. Wang, J. Qi, W. Cui, L. Deng. Bioinspired Functional Black Phosphorus Electrospun Fibers Achieving Recruitment and Biomineralization for Staged Bone Regeneration. Small 16 (2020).
6. Q. Saiding, J. Jin, M. Qin, Z. Cai, M. Lu, F. Wang, W. Cui, X. Chen. Heat-Shrinkable Electrospun Fibrous Tape for Restoring Structure and Function of Loose Soft Tissue. Adv. Func. Mat. 26 (2020).
7. M. Lu, T. Dai, S. Hu, Q. Zhang, B. Bhayana, L. Wang, M. X. Wu, Antimicrobial blue light for decontamination of platelets during storage. J Biophotonics 13, e201960021 (2020).
8. L. G. Leanse, P. T. Dong, X. S. Goh, M. Lu, J. X. Cheng, D. C. Hooper, T. Dai, Quinine enhances photo-inactivation of Gram-negative bacteria. J. Infect. Dis. 221, 618-626 (2020).
9. Q. Zhang, M. Lu, M. X. Wu, Potentials for prolonging shelf-life of platelets by near infrared low-level light. J Biophotonics 12, e201800390 (2019).
10. M. Lu, T. Dai, M. X. Wu, Synergistic inactivation of multidrug-resistant Pseudomonas aeruginosa by essential oil and blue light. (Society of Photo-Optical Instrumentation Engineers (SPIE) Conference Series, San Francisco, California, US). vol. 10863 (2019).
11. M. Lu, P. Li, Q. Zhang, Y. Yu, S. Wen, M. X. Wu, Potentials of noninvasive low-level laser therapy for neonatal thrombocytopenia. (Society of Photo-Optical Instrumentation Engineers (SPIE) Conference Series, San Francisco, California, US). vol. 1086109 (2019).
12. M. Lu, T. Dai, C. K. Murray, M. X. Wu, Bactericidal property of oregano oil against multidrug-resistant clinical isolates. Front. Microbiol. 9, 2329 (2018).
13. I. Ahmed, Y. Fang, M. Lu, Q. Yan, A. El-Hussein, M. R. Hamblin, T. Dai, Recent patents on light-based snti-infective approaches. Recent Pat. Antiinfect. Drug Discov. 12, 70-88 (2018).
14. Y. Wang, X. Wu, J. Chen, R. Amin, M. Lu, B. Bhayana, J. Zhao, C. K. Murray, M. R. Hamblin, D. C. Hooper, T. Dai, Antimicrobial blue light inactivation of Gram-negative pathogens in biofilms: in vitro and in vivo studies. J. Infect. Dis. 213, 1380-1387 (2016).
15. X. Li, M. Lu, D. Tang, Y. Shi, Composition of carotenoids and flavonoids in Narcissus cultivars and their relationship with flower color. PloS One 10, e0142074 (2015).
16. M. Lu, Z. Han, L. Yao, In vitro and in vivo antimicrobial efficacy of essential oils and individual compounds against Phytophthora parasitica var. nicotianae. J. Appl. Microbiol. 115, 187-198 (2013).
17. M. Lu, Z. Han, Y. Xu, L. Yao, Effects of essential oils from Chinese indigenous aromatic plants on mycelial growth and morphogenesis of three phytopathogens. Flavour Frag. J. 28, 84-92 (2013).
18. M. Lu, Z. Han, Y. Xu, L. Yao, In vitro and in vivo anti-tobacco mosaic virus activities of essential oils and individual compounds. J. Microbiol. Biotechnol. 23, 771-778 (2013).
授权专利
1. 缓解精油疲劳的芳香精油固体组合物及其制备方法，申请号：201210541757.2，姚雷，卢敏，杨森艳，徐建华，姚伟平
2. 一种防治烟草花叶病毒的精油制剂及其应用，专利号：ZL201110429845.9，韩智强，高则睿，卢敏，姚雷，徐云，李忠环，彭云，高福宏，詹莜国
3. 防治烟草真菌性病害的精油药剂及其使用方法，专利号：ZL201110404047.0，姚雷，卢敏，韩智强，李忠环，徐云，詹莜国，彭云
4. 水仙花中β-胡萝卜素的提取分离方法，专利号：ZL201410253476.6，李欣，史益敏，卢敏